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Acute, subacute and chronic toxicities affect many organs and systems in the body (Fig
This focus led to significant breakthroughs, but it became clear in animal models that single-pathway stimulation had a ceiling effect regarding metabolic stabilization and lipid management
The first objective landmark I rely on is the peak reticulocyte count 1 week after starting treatment
These options are not available to everyone and come with their own trade-offs, but they deserve consideration when injection site reactions significantly impact quality of life
doi:10.1016/j.abb.2016.01.017
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